Asin debuted in a supporting role in a Malayalam film Narendran Makan Jayakanthan Vaka in 2001 at the age of 15. After one year she was back again with a blockbuster Telugu Film Amma Nanna O Tamil Ammayi with famour Telugu Hero Ravi Teja. In that telugu movie she acted as a Tamil Girl, which subsequently fetched her the Telugu Filmfare Award fo Best Actress. In the same year she won the Santhosham Best Actress Award for her performance.